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97/05/15: AIDS Daily Summary

                     AIDS Daily Summary 

                        May 15, 1997

     

The CDC National Center for HIV, STD, and TB Prevention makes 

available the following information as a public service only. 

Providing this information does not constitute endorsement by the 

CDC. Reproduction of this text is encouraged; however, copies may 

not be sold, and the CDC National AIDS Clearinghouse should be 

cited as the source of this information. Copyright 1997, 

Information, Inc., Bethesda, MD

     

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"Doctor Plans to Open Profit-Making Centers for Treatment of AIDS 

and H.I.V. Patients"

"Vaccine for HIV Might Always Elude Researchers' Efforts" 

"Tuskegee Survivors Make Trek to Capital for Apology" 

"Health-Care Entrepreneur Plans to Open a Chain of For-Profit 

AIDS Clinics: [NY Blood Center to Close Test Lab]"

"New Study Downplays Medical Benefit of Marijuana" 

"White House Backs AIDS Amendment"

"AIDS List Sender Gets 60 Days in Jail"

"Prostitution Crimes: Bill Would Force More Testing for HIV" 

"AIDS Trials Ethics Questioned"

"Urinary Stones in HIV-1-Positive Patients Treated With 

Indinavir"

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"Doctor Plans to Open Profit-Making Centers for Treatment of AIDS 

and H.I.V. Patients"

New York Times (05/15/97) P. A35; Fein, Esther B.

     Dr. Bernard Salick, the entrepreneur that brought for-profit

cancer treatment to New York, plans to launch a chain of 

for-profit AIDS and HIV treatment centers in the city within the 

next three months.  Salick has already enlisted Dr. David Ho, 

director of the Aaron Diamond AIDS Research Center in Manhattan, 

and is in negotiations with several New York medical centers in 

an effort to find a location.  Ho will serve as Salick's 

principle adviser, while retaining his current position as 

director of the Aaron Diamond AIDS Research Center in Manhattan. 

Salick's long-term plans include finding a vaccine and cure for 

AIDS, and opening additional treatment centers in Los Angeles, 

Miami, and San Francisco.

     

"Vaccine for HIV Might Always Elude Researchers' Efforts" 

Washington Times (05/15/97) P. A10; Price, Joyce

     Robert Gallo, co-discoverer of HIV and director of the

University of Maryland's Institute of  Human Virology, said on 

Tuesday that scientists may never develop an effective vaccine 

against HIV.  The remarks, made at a vaccine symposium held in 

Washington D.C., were later followed by comments from Gallo that 

indicated he did believe a vaccine would eventually be found. 

Nevertheless, the contention among many AIDS researchers is that 

developing a vaccine against the virus that causes AIDS is likely, 

but difficult, and not in the immediate future.  "Because of the 

difficulties, I said that I couldn't see we'd have one before the 

beginning of the 21st century," said Anthony Fauci, director of the 

National Institute of Allergy and Infectious Diseases.

     

"Tuskegee Survivors Make Trek to Capital for Apology" 

USA Today (05/15/97) P. 6A; Kasindorf, Martin

     Despite entreaties from the elderly survivors of the

Tuskegee syphilis study for President Clinton to deliver his 

apology for the event in Alabama, where it took place, the 

apology will be delivered in the White House Rose Garden.  As a 

result, only four of the eight survivors of the racist study will 

be in attendance on Friday--Charlie Pollard, age 91; Carter 

Howard, 93; Herman Shaw, 94; and Fred Simmons, 100.  The U.S. 

Centers for Disease Control and Prevention will cover their 

travel expenses, while providing a satellite telecast to the four 

frailest survivors who will remain in Tuskegee.

     

"Health-Care Entrepreneur Plans to Open a Chain of For-Profit 

AIDS Clinics: [NY Blood Center to Close Test Lab]"

New York Times (05/15/97) P. A34; Altman, Lawrence K.

     Officials of the New York Blood Center said Wednesday that

the center will close its Manhattan laboratory responsible for 

screening blood for such infectious diseases as HIV, hepatitis, 

and syphilis, and outsource the testing to an independent lab.  

The lab will close within 60 to 90 days, though the blood center 

will remain open.  The blood center collects and distributes 

approximately 85 percent of the blood products supplied to the 

greater New York area.  Allegations of improper testing 

procedures at the lab first circulated last November.  In 

December, the blood center entered a consent decree with the FDA 

to institute changes needed to bring it into compliance with 

federal laws and regulations

     

"New Study Downplays Medical Benefit of Marijuana" 

Baltimore Sun (05/15/97) P. 11A

     New research published in Wednesday's edition of the Annals

of Internal Medicine suggests that smoking marijuana has less 

medical benefit than taking the drug's active ingredient, THC, in 

its pure form, which is the prescription drug dronabinol.  

Moreover, neither is beneficial when side effects are taken into 

account.  Researchers from the International Drug Strategy 

Institute, an anti-drug think tank, noted that THC has been shown 

to be useful for such things as fighting nausea after chemotherapy 

and increasing appetite in AIDS patients, but its medical value is 

limited by its intoxicating effects.  At least one proponent of 

the use of marijuana for medical purposes said the study's authors 

were biased.

     

"White House Backs AIDS Amendment"

Washington Times (05/15/97) P. A10

     A House amendment to the $5.5 billion flood disaster bill

has been proposed by Rep. Nancy Pelosi (D-Calif.) and backed by 

the White House.  The amendment would provide an additional $68 

million to a program that offers AIDS drugs to low-income 

patients.

     

"AIDS List Sender Gets 60 Days in Jail" 

Washington Times (05/15/97) P. A10

     Gregory Wentz, the former funeral home director found guilty

of sending a confidential list of some 4,000 AIDS patients to the 

media to spite a former lover, has been sentenced to 60 days in 

prison.  He will remain free pending his appeal.

     

"Prostitution Crimes: Bill Would Force More Testing for HIV" 

St. Louis Post-Dispatch (05/14/97) P. 2B

     A bill sent by the Missouri legislature to Gov. Mel Carnahan

would make HIV-testing a potential bond requirement for anyone 

arrested more than once for prostitution-related crime.  The bill 

would also clarify the state's laws regarding reckless spread of 

HIV, and would boost penalties for adults who willfully infect 

minors.

     

"AIDS Trials Ethics Questioned"

Science (04/25/97) Vol. 276, No. 5312, P. 520; Cohen, Jon

     With the remarkable success of new AIDS treatment options,

AIDS researchers and drug testers face the ethical dilemma of 

whether it is wrong to provide patients with trial drugs that are 

less effective than the proven therapies.  Even as the AIDS 

treatment community strives to overhaul the nature of its trials, 

many critics say too often drug developers knowingly conduct 

tests focusing on "suboptimal" therapies.  Joep Lange, of the 

University of Amsterdam, has been particularly scathing in his 

criticism of drug developers.  Citing the consensus that 

combination therapies have proven most successful delaying drug 

resistance in AIDS patients, Lange and other like-minded 

researchers say that tests lacking this approach are unethical 

and endanger patients.  Other researchers contest this view, 

saying that since anti-HIV drugs affect everybody differently, 

clinical trials must focus on a wide array of treatment options 

to establish which option is best for each patient.  Thus, a 

treatment with moderate anti-HIV power must still be tested 

because it could turn out to be a valuable weapon against the 

disease due a particular patient's physiological disposition or 

history of treatment.

     

"Urinary Stones in HIV-1-Positive Patients Treated With 

Indinavir"

Lancet (05/03/97) Vol. 349, No. 9061, P. 1294; Daudon, M.; 

Estepa, L.; Viard, J. P.; et al.

     Researchers recently studied indinavir sulphate, a protease 

inhibitor, as part of a combination treatment for HIV-1-positive 

patients.  They found that more than 100 HIV-infected patients of 

a large therapeutic program in France developed renal colic 

and/or passed radiolucent urinary stones within one to 20 weeks 

after the initiation of treatment.  Only three of the patients 

had a past history of urinary stones.  The occurrence of the 

stones, however, was not an unexpected event, as the risk has 

been noted in a document from the European Agency for the 

Evaluation of Medicinal Products.






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