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The Ebola Virus
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and the Challenges to Health Research in Africa
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answer than the grandiose philosophical ones, perhaps because we expect
a more concrete answer. I try to put Ebola in the context of the great
burden of health problems of Africa. What does it mean? As a researcher
and a health care worker,
Although perhaps one of the most dramatic, Ebola is far from being
the biggest threat to health in sub-Saharan Africa. Sometimes, it seems
that Africa almost courts misery, reading like the script of a bad action
movie, everything happening at once-disease, natural disasters, war,
epidemics-a Hollywood producer would likely throw it out as too unbelievable.
As the Ebola epidemic started to wane, I finally had a few minutes to
get to know some of my co workers-the human beings behind the surgical
masks.
To survive to old age in much of sub-Saharan Africa, it seems you have
to run the gauntlet. Only a strong disposition, and perhaps a good dose
of luck, buys you longevity. Children survive the respiratory and diarrhoeal
illnesses of childhood, only to face new threats of AIDS and Ebola,
wars and automobile accidents. Too often, if one thing doesn't get you,
another will. Dr. Matthew was once abducted by the Lord's Resistance
Army-a rebel group active in northern Uganda-held for a few days and
then released. He survived that round, but wasn't so fortunate in the
Ebola category.
When something as dramatic and deadly as Ebola breaks out, a host of resources are mobilized and a United Nations-worth of organizations converge on the epicentre to help put out the fire. They generally do an effective job, but return just a few months later and one usually finds that it's back to business as usual. Short-term financial commitments for a high-profile outbreak are relatively easily forthcoming, but long-term support for the public health infrastructure necessary to truly understand the epidemiology of these diseases, and thus possibly prevent them in the future, is scarce. This is unfortunate, as long-term investigations exploring their natural history-where they come from, how they are transmitted from one person to another-would ultimately have far more of an impact on health than the measure of our emergency response to any single given outbreak. The point is not that one is more important than the other, but rather that if there was more of the former, there would be a lot less need for the latter. What are the impediments to long-term scientific research in developing countries and, through it, better health? An initial, fundamental but perhaps philosophical, question harkens back to a debate that has raged since the late eighteenth century when politicians argued over whether the new United States of America should be an "isolationist" or "interventionalist" nation. "Globalization" being the word of the day, it seems the latter sentiment has prevailed. But while we perhaps accepted this economically, we have stopped short of a true commitment to health on a global scale. Rather, we are witness to a call to return to a sort of bioscience "isolationism", with Governments of many industrialized countries reorienting their budgets toward those health problems deemed to be in the "national interest".
But whereas nations have boundaries, pathogens have none. With regard to health and disease, what national interest can be separated from our collective international one? Examples of this connection are rife: the importation of West Nile encephalitis into the United States in 1999, a patient with Lassa fever transported from West Africa to Chicago, protection from the threat of biological warfare. Myriad arguments can be made to support how engagement overseas can lead to increased economic and political stability and improved health for all. But even if we discount them, does a rich nation really need a reason to engage with a poor one? If researchers at many African institutions have little to do these
days, it is not
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